If you can, I highly recommend you try it out. There’s relatively inexpensive tube amps, even on Amazon that you could play with and box back up if it’s not your cup of tea. I just looked at the compressor I use and the price has gone up to a point where it doesn’t make much sense anymore, but it is SUPER useful to add some warmth in between a digital source and the class d amps I use in my PA system.
I’m curious if you’ve tried listening to lossy compressed audio through a vacuum tube output stage? I use a cheap tube compressor with the attack and release turned to minimal and just a little bit of extra makeup gain so that the tube colors the audio a small amount. Think of it like sanding the layer lines of a 3d print, but for audio. It does introduce a small amount of hiss and colors the midrange a bit more prominently, but you can eq that out.
If you are using the files played back at different tempos or keyshifted, the difference between lossy and lossless is a lot more apparent. For standard playback at normal pitch, mp3 is just fine.
Swapping out tubes (and opamps on your DAC) is very much a thing, and I’m convinced that I can hear the difference between a sovtek tube and a Chinese clone, but that could be all in my head, as it wasn’t a blind test. Do some research on the amps, but for computer use, Fosi mc331 has an integrated DAC and puts out about 100w per channel. If my computer didn’t already have active studio monitors, I’d have pulled the trigger on it by now. For $116, it’s hard to resist.